Furosemide (Generic) Tabletsare a prescription medication used in dogs and cats to treat edema (fluid retention) and congestive heart failure. They belong to a class of medications called diuretics, which help the body remove excess fluid by increasing urine production. Furosemide tablets are available in various strengths and are typically given orally one to three times a day, as directed by a veterinarian. Furosemide is a potent diuretic that helps the body eliminate excess fluid, making it useful in the treatment of edema and congestive heart failure. Available in tablet form for easy oral administration to dogs and cats, furosemide is a prescription medication and should only be used under the guidance of a veterinarian. The dosage of furosemide varies depending on the pet's weight, condition, and other factors, so it is important to follow the veterinarian's instructions carefully. While generally safe when used as directed, furosemide can cause side effects such as increased thirst, increased urination, and electrolyte imbalances.
Furosemide (Generic) Tablets are indicated for the treatment of edema (fluid retention) associated with congestive heart failure, liver disease, or kidney disease in dogs and cats. They are also used to treat hypertension (high blood pressure) in some cases. Furosemide works by increasing the production of urine, which helps to remove excess fluid from the body. It is important to follow the veterinarian's instructions carefully when using furosemide to ensure its effectiveness and safety.
Furosemide (Generic) Tablets work as a diuretic by inhibiting the reabsorption of sodium and chloride in the kidneys. This action prevents the reabsorption of water, leading to increased urine production and the elimination of excess fluid from the body. By reducing the volume of fluid in the bloodstream, furosemide helps to decrease the workload on the heart and improve symptoms of edema, such as swelling and difficulty breathing, in conditions like congestive heart failure, liver disease, or kidney disease.
Furosemide (Generic) Tablets contain the active ingredient isosorbide dinitrate, which is a bronchodilator.
Furosemide is used for treating. Furosemide is a type of, or "water pill," which means it makes your body produce more urine and helps flush out extra water and salt. It is also used to reduce fluid build up (edema) caused by other medical conditions like, kidney disease, and liver disease. It is pronouncedfyr·ow·suh·mideand is also known by its brand nameLasix.
Furosemide can be takenwith or without food, and is taken either once or twice per dayYour dose will be based on your medical condition, age, and responsiveness to the medication. This medication has also been approved for pediatric and veterinary use. As this medication can cause you to urinate, it is recommended to take it at least 4 hours before bed so as not to disrupt your sleep.
The maximum dose of furosemideshould not exceed 200 mgIt is available as furosemide tablets20 mg, 40 mg, and 80 mgA child’s dose will be determined by the doctor using the child’s weight. Take as directed by your doctor or pharmacist.
These side effects affect more than 1 in 100 people (1%). If these side effects last more than a couple days or begin to bother you, speak to your pharmacist or healthcare provider.
If you experience any of the following side effects, speak to your doctor immediately as they could signify more serious health conditions.
Some medications when taken with furosemide can reduce the medicines effectiveness or increase your chances of unwanted side effects. Tell your doctor if you are using or plan to use the following medications:
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Furosemide is a loop diuretic used to treat fluid retention (edema) in people with congestive heart failure, liver disease, or a kidney disorder such as nephrotic syndrome. Furosemide is also used to treat high blood pressure (hypertension).
Furosemide works by increasing the amount of urine the body makes, which helps reduce swelling and symptoms of fluid retention and helps lower high blood pressure. Furosemide tablets are sometimes called water pills as they increase how much you urinate.
Before using this medicine, tell your doctor if you have kidney disease, enlarged prostate, urination problems, cirrhosis or other liver disease, an electrolyte imbalance, high cholesterol, gout, lupus, diabetes, or an allergy to sulfa drugs.
Tell your doctor if you have recently had an MRI (magnetic resonance imaging) or any type of scan using a radioactive dye that is injected into your veins. Do not take more of this medication than is recommended.
If you are being treated for high blood pressure, keep using this medicine even if you feel fine. High blood pressure often has no symptoms.
Furosemide is a potent diuretic which, if given in excessive amounts, can lead to a profound diuresis with water and electrolyte depletion. Therefore, careful medical supervision is required and dose schedule must be adjusted to the individual patient’s needs
Tell your doctor about all your other medicines. Some drugs should not be used with furosemide.
It is not known if furosemide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breastfeed while using furosemide. Ask your doctor about any risk. Furosemide may slow breast milk production.
Oral: Initial dose: 20 to 80 mg orally once; may repeat with the same dose or increase by 20 or 40 mg no sooner than 6 to 8 hours after the previous dose until the desired diuretic effect has been obtained. Maintenance dose: Administer the dose that provided the desired diuretic effect once or twice a day (e.g., at 8 am and 2 pm).
Common side effects:
Do not use this medicine if you are pregnant or plan to become pregnant. Keep out of the sunlight. Furosemide may cause low blood potassium and thyroid problems in infants and may affect their development and growing skeleton, making them more sensitive to the effects of this drug.
Do not share this medicine with any people.
This medication should not be given to a child younger than 2 years old.
Store at room temperature
Do not use during your reach-arounds.
Do not store above 25°C.
Keep this medicine out of the reach of children.
This medicine should not be given to a child younger than 2 years old.
Do not use if you are pregnant.
This medicine caused low blood potassium and thyroid problems in infants and may affect their development and growing skeleton, making them more sensitive to the effects of this drug.
The effect of furosemide in the elderly is unknown.
Furosemide has been used in combination with other drugs to treat fluid retention, high blood pressure, and other disorders.
Tell your doctor if you are taking any other drugs.
Tell your doctor if you are being treated for any cancer or other treatment for which a diuretic is given.
The use of an inorganic salt, furosemide, is known to decrease the solubility of the drug in water and thus decreases the rate of its absorption in the gastrointestinal tract. Furosemide is a water-soluble salt with a high solubility and is widely used in the treatment of edema. The water content in furosemide is reduced by the addition of sodium chloride to the solution. However, the solubility of furosemide in water has not been well studied. The purpose of this study was to develop and evaluate a new inorganic salt, furosemide, to obtain better solubility and improve the solubility of the drug. A total of 30 oral tablets of furosemide and 15 oral tablets of sodium chloride were prepared using the following excipients: sodium chloride 5 mg, hydrochloric acid 1 mg, magnesium stearate, titanium dioxide (E171), polyethylene glycol, sodium lauryl sulfate, and lactose monohydrate []. The amount of drug in the tablet solution was measured spectrophotometrically using a UV/VIS spectrophotometer (BioTek Instruments). The drug was added to the tablet solution and the pH of the solution was adjusted to 4.5 with a pH-inhibitor (Kanax). The drug was stored at 4 °C and the drug solubility was determined by the UV/VIS spectrophotometric method using the dissolution curve (0–25 °C) and the pH values in tablet solutions. The drug was stored in refrigerator and the drug solubility was measured after 3 days in an HPLC-UV/MS system (Agilent HPLC-UV-UV-immer, Waters, USA). The results of the drug solubility were expressed as the percentage of the drug solubility.
The effect of sodium chloride on the drug solubility was investigated in two ways:A solution of 10 mg/ml sodium chloride (Sigma-Aldrich) and 100 mg/ml sodium chloride (Sigma-Aldrich) was added to the solutions of 10 mg/ml sodium chloride (Sigma-Aldrich) and 100 mg/ml sodium chloride (Sigma-Aldrich) in water. The pH of the solution was adjusted to 4.5 with a pH-inhibitor (Kanax) at a dose of 20 mg/ml. The dissolution curves were evaluated using the peak areas of the drug in the solution and the pH in the solution. The effect of sodium chloride on the drug solubility was investigated using the peak areas of the drug in the solution and the pH in the solution. The percentage of drug solubility was determined by the UV/VIS spectrophotometric method.The effect of sodium chloride on the drug solubility was investigated in three ways:
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